Isaac Guerendo of the San Francisco 49ers suffered a foot injury during the fourth quarter of the game against the Chicago Bears, leaving his status questionable for the remainder of the game. Prior to his exit, Guerendo was having a strong performance, contributing significantly to the team's rushing attack and also making plays in the passing game. His injury raises concerns for the 49ers' backfield depth moving forward.
- Isaac Guerendo was having a breakout performance before his injury.
- The 49ers may need to rely on backup RBs Patrick Taylor and Israel Abanikanda moving forward.