Joe Mixon is listed as doubtful for the upcoming game against the Vikings due to an ankle injury, having not practiced throughout the week. This opens the door for Cam Akers to take on a larger role in the Texans' backfield. Earlier in the offseason, Mixon had expressed confidence in his training and expected workload for his first season with the Texans after leaving the Bengals.

• Joe Mixon is doubtful for Sunday, impacting fantasy lineups.
• Cam Akers may be a viable fill-in option for Mixon.
• Mixon trained harder than ever in anticipation of a heavy workload.