The Houston Texans are facing uncertainty with their running backs as Joe Mixon and Dameon Pierce both missed practice on Wednesday. Mixon, who is dealing with an ankle issue, had shown some progress with a limited practice last week, but his status for the upcoming game against the Bills is now in doubt. Similarly, Pierce is also struggling with a hamstring injury, which could impact the Texans' backfield depth for the game.
- Both Mixon and Pierce are key players for the Texans, and their injuries could significantly affect the team's offensive strategy.
- The Texans may need to rely on other players if both Mixon and Pierce are unable to play.