Jonathan Taylor, the star running back for the Indianapolis Colts, has been ruled out for Week 5 due to a right ankle sprain he sustained in the previous game against the Steelers. Coach Shane Steichen confirmed that Taylor did not practice leading up to the game against the Jaguars. Trey Sermon and Tyler Goodson are expected to lead the backfield in his absence. Despite the injury, Taylor had a strong performance in Week 4, accumulating 108 yards from scrimmage and scoring his fourth rushing touchdown of the season.

• Jonathan Taylor will miss at least one game due to an ankle injury.
• Trey Sermon and Tyler Goodson will take over the Colts' backfield duties.