Isaac Guerendo, running back for the San Francisco 49ers, has been cleared to play in Week 17 against the Detroit Lions after recovering from foot and hamstring injuries. He had previously missed Week 16 due to a severe hamstring injury but is expected to lead the 49ers' backfield following a strong performance in Weeks 14 and 15, where he accumulated significant touches and yardage.
- Guerendo is set to return after missing one game due to injury.
- He had a strong performance prior to his injury, making him a key player for the 49ers.