San Francisco 49ers running back Christian McCaffrey is set to miss his second consecutive game due to ongoing calf and Achilles issues. Coach Kyle Shanahan indicated that McCaffrey experienced significant pain, marking his worst health day on Thursday. The team is now considering placing him on injured reserve, which would sideline him for at least four games.
- McCaffrey's health continues to be a concern for the 49ers.
- The possibility of injured reserve could severely impact his fantasy value.