With Jonathan Taylor ruled out due to an ankle injury, Trey Sermon is expected to take on the lead role in the Indianapolis Colts' backfield for their Week 6 matchup against the Tennessee Titans. Sermon has shown promise in his limited opportunities, notably scoring a touchdown and accumulating 63 scrimmage yards in Week 5 against the Jaguars.
- Trey Sermon is set to lead the Colts' backfield in Week 6.
- Jonathan Taylor's absence opens the door for Sermon to showcase his skills.