Pittsburgh Steelers quarterback Kenny Pickett sustained an ankle injury during the game against the Arizona Cardinals and will not return. He injured his ankle when he scrambled forward and was tackled from behind. Pickett had previously been dealing with right ankle discomfort. Quarterback Mitch Trubisky took over for the second half. The Steelers also ruled out inside linebacker Elandon Roberts and left guard Isaac Seumalo for the remainder of the game.