Pittsburgh Steelers wide receiver George Pickens has been ruled out for the upcoming game against the Philadelphia Eagles due to a Grade 2 hamstring strain. He did not practice throughout the week, raising concerns about his availability for future games. With Pickens sidelined, the Steelers' wide receivers are not recommended for fantasy football, while tight end Pat Freiermuth is expected to see increased opportunities.

• George Pickens is out for Week 16 due to a hamstring injury.
• Pat Freiermuth is likely to benefit from increased targets with Pickens unavailable.
• The Steelers' wide receivers are not advisable for fantasy lineups against the Eagles.