The Los Angeles Chargers have placed running back Gus Edwards and cornerback Asante Samuel Jr. on injured reserve, meaning they will miss at least the next four games. Samuel's injury came as a surprise, as he practiced all week but was ruled out on Friday. The Chargers' secondary is already struggling with injuries, and the absence of both Samuel and starting nickel cornerback Ja'Sir Taylor will force rookie cornerbacks into larger roles. Edwards, dealing with an ankle injury, will also be sidelined, leading to increased responsibilities for other running backs on the roster.

• Both Gus Edwards and Asante Samuel Jr. will miss at least four games due to injuries.
• The Chargers' secondary is heavily impacted with multiple injuries, leading to increased roles for rookie cornerbacks.
• Rookie running back Kimani Vidal is expected to be active for the first time this season.