Isaac Guerendo, a rookie running back for the San Francisco 49ers, showcased his potential in a recent game against the Seattle Seahawks, rushing for 99 yards on 10 carries. With Jordan Mason sidelined due to injury, Guerendo stepped up as the lead back in the second half, including a notable 76-yard run. His performance raises questions about his role moving forward, especially with the upcoming game against the Kansas City Chiefs.

• Isaac Guerendo had a breakout performance with increased volume due to injuries in the backfield.
• His 76-yard run highlights his explosive speed and potential as a lead back.