The Buffalo Bills will be without rookie wide receiver Keon Coleman for their upcoming game against the Indianapolis Colts due to a wrist injury sustained in Week 9. Coach Sean McDermott indicated that while Coleman will not be placed on injured reserve, his absence adds to the team's struggles with injuries in the wide receiver position. Amari Cooper is also questionable for the game as he continues to recover from his own wrist injury.
- The Bills are facing significant challenges in their receiving corps with multiple injuries.
- Keon Coleman is expected to return before the four-week minimum for injured reserve.