In this article, Mel Kiper Jr. evaluates every No. 1 NFL draft pick since 1979, categorizing them into tiers based on their performance and impact on their respective teams. The analysis includes a breakdown of elite picks, solid starters, and disappointments, with a focus on the four best No. 1 picks. Kiper emphasizes the importance of evaluating both the draft selection and the player's contributions to the franchise over time.

• Kiper has evaluated 46 No. 1 picks since 1979, categorizing them into tiers.
• Peyton Manning is regarded as the best No. 1 pick during Kiper's analysis period.