In Week 6 of the NFL, divisional matchups led to some entertaining social media trolling, particularly from the Tampa Bay Buccaneers after their dominant victory over the New Orleans Saints. The Buccaneers scored 51 points, with Baker Mayfield throwing for 325 yards and four touchdowns. Other notable games included the Indianapolis Colts narrowly defeating the Tennessee Titans, the Houston Texans spoiling Drake Maye's debut with the New England Patriots, and the San Francisco 49ers overcoming the Seattle Seahawks.

• The Buccaneers showcased a powerful offense, scoring 51 points against a divisional rival.
• Baker Mayfield's performance was notable despite his interceptions.
• The Colts and Texans both secured important divisional wins.