Joe Mixon is currently not practicing due to an ankle injury, raising concerns about his availability for the upcoming game against the Bills. Despite this setback, Mixon has expressed confidence in his preparation for a significant role in the Texans' offense this season, having trained harder than ever during the offseason. With limited competition for carries, he aims to replicate his previous high-carry seasons.

• Joe Mixon is not practicing due to an ankle injury.
• Mixon is preparing for a heavy workload in his first season with the Texans.