Colts running back Jonathan Taylor is not expected to practice on Wednesday due to an ankle injury, casting doubt on his availability for the upcoming game against the Titans. With Taylor likely to miss the game, the Colts will rely on Trey Sermon and Tyler Goodson to carry the load in the backfield. In their previous game against the Jaguars, Sermon had a more significant role with 10 carries and six targets compared to Goodson's five carries and three targets.
- Jonathan Taylor's absence could significantly impact the Colts' offense.
- Trey Sermon and Tyler Goodson are set to take over the backfield duties.