Colts wide receiver Alec Pierce will miss the upcoming game against the Titans due to a concussion. This absence opens up opportunities for fellow receivers Michael Pittman and Josh Downs, who are expected to see an increase in targets. Additionally, Adonai Mitchell is likely to take over most of Pierce's snaps, although he is considered a risky option primarily for DFS tournaments.

• Alec Pierce's absence boosts the target share for Michael Pittman and Josh Downs.
• Adonai Mitchell is a potential fill-in but is best suited for DFS tournaments.