Jonathan Taylor continues to be sidelined due to a right high ankle sprain, missing practice and games since Week 4. His absence raises concerns for the Colts' backfield, with Trey Sermon expected to take on the primary running back role if Taylor cannot return. The Colts are hoping for a boost from quarterback Anthony Richardson's return, which could help their ground game.
- Jonathan Taylor remains out with an ankle injury, impacting the Colts' offensive strategy.
- Trey Sermon is poised to lead the backfield in Taylor's absence.