Buffalo Bills wide receiver Keon Coleman has been ruled inactive for the upcoming game against the San Francisco 49ers due to a wrist injury. Despite being limited in practice throughout the week, Coleman will aim for a return in Week 14. In his absence, the Bills will rely on other receivers including Khalil Shakir, Amari Cooper, Curtis Samuel, and Mack Hollins.

• Keon Coleman is dealing with a wrist injury and is inactive for the game.
• The Bills will utilize a mix of other wide receivers in Coleman's absence.