San Francisco 49ers quarterback Brock Purdy is expected to return for the game against the Buffalo Bills after recovering from a shoulder injury. Coach Kyle Shanahan indicated that Purdy has made significant progress and is likely to play unless there are any setbacks. However, the 49ers will be without key players including left tackle Trent Williams and defensive end Nick Bosa due to injuries. Cornerback Charvarius Ward is set to return after a personal absence.
- Brock Purdy is likely to return, providing a boost to the 49ers' offense.
- The absence of Trent Williams and Nick Bosa will challenge the 49ers' line and defense.
Brock Purdy | QB

Injury
Pickup
Week 13
- Purdy is expected to play against the Bills after recovering from a shoulder injury.
- He was a full participant in practice leading up to the game.
San Francisco 49ers

- The 49ers face challenges with key players injured but are hopeful with Purdy's return.
- The offensive line will need to adjust without Williams and Banks.