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The San Francisco 49ers are facing significant injury challenges ahead of their upcoming game against the Los Angeles Rams. Tight end George Kittle is doubtful due to a sore hamstring, having missed the final two practices of the week. With Kittle, along with running back Christian McCaffrey and wide receiver Deebo Samuel, sidelined, the 49ers will need to rely on other players to step up, including running back Jordan Mason and wide receiver Brandon Aiyuk. Tight end Eric Saubert is expected to take over Kittle's role, but he may not be a reliable fantasy option.
- 49ers are missing key offensive players this week.
- Kittle's absence will impact the team's passing game significantly.
- Jordan Mason and Brandon Aiyuk are set to take on larger roles.
George Kittle | TE
Injury
Week 6
- Listed as doubtful for the game against the Rams due to a hamstring injury.
- Missed the final two practices of the week.
Brandon Aiyuk | WR
Breakout
Week 6
- Will see increased targets and opportunities with Kittle and Samuel out.
San Francisco 49ers
- Facing a tough matchup against the Rams without key offensive players.
- Will need to rely heavily on remaining skill players to generate offense.