The San Francisco 49ers have reached a five-year, $170 million contract extension with defensive end Nick Bosa, making him the highest-paid defensive player in the league. Bosa's holdout has ended, and he is expected to play in the season opener against the Pittsburgh Steelers. Despite the holdout, Bosa's rankings in fantasy football have not been affected, as he has previously shown his ability to perform well even with limited practice time.

• Nick Bosa has signed a five-year, $170 million extension with the 49ers.
• The contract makes Bosa the highest-paid defensive player in the league.
• Bosa's holdout has ended, and he is expected to play in the season opener against the Steelers.
• Despite the holdout, Bosa's fantasy football rankings have not been affected.