Jonathan Taylor continues to be sidelined due to an ankle injury, missing practice ahead of the Colts' upcoming game against the Titans. After sitting out the previous game against the Jaguars, his ability to return remains uncertain as he has not yet practiced this week. If he cannot play, Trey Sermon and Tyler Goodson are expected to take over the backfield duties for the Colts.
- Jonathan Taylor's status is uncertain as he has not practiced due to an ankle injury.
- Trey Sermon is expected to start if Taylor is unable to play again.