The NFL's Week 3 schedule features a mix of intriguing matchups, highlighted by a Thursday night clash between the New England Patriots and New York Jets, and a Monday Night Football doubleheader featuring the Jacksonville Jaguars at the Buffalo Bills and the Washington Commanders at the Cincinnati Bengals. With several games showcasing significant point spreads, this week promises to deliver exciting action on the field.

• Seven of the 16 matchups have a favorite giving up at least 6.5 points to the underdog.
• The highest total of the week is for the Lions vs. Cardinals game at 51.5.
• The lowest total is for the Steelers vs. Chargers game at 36.5.