The Indianapolis Colts will be without star running back Jonathan Taylor for their upcoming game against the Jacksonville Jaguars. Taylor, who is currently the fifth-leading rusher in the league, suffered an ankle injury during the previous game against the Pittsburgh Steelers and did not practice all week. Meanwhile, quarterback Anthony Richardson's status is uncertain after dealing with a hip/oblique bruise, and if he cannot play, veteran Joe Flacco will take over the starting role. The Colts are also missing cornerback Kenny Moore and defensive end Kwity Paye due to injuries.

• Jonathan Taylor's absence is a significant blow to the Colts' offense.
• Anthony Richardson's injury status adds uncertainty to the Colts' quarterback situation.
• Joe Flacco's performance as a backup could be crucial if Richardson is unable to play.