Joe Mixon and Dameon Pierce, both running backs for the Houston Texans, did not practice on Wednesday due to their respective injuries. While Mixon's ankle injury is not deemed serious, his availability for the upcoming game against the Vikings remains uncertain. Similarly, Pierce's hamstring issue puts his participation in jeopardy. If both are unable to play, Cam Akers is expected to take on the early-down role, with Dare Ogunbowale handling some passing situations.
- Both Joe Mixon and Dameon Pierce are dealing with injuries that could impact their availability for the upcoming game.
- If Mixon and Pierce are out, Cam Akers will step up as the primary running back.
Joe Mixon | RB

Injury
Week 5
- Did not practice on Wednesday due to an ankle injury.
- His injury is not serious, but his status for the game against the Vikings is uncertain.
Dameon Pierce | RB

Injury
Week 5
- Did not practice on Wednesday due to a hamstring injury.
- His availability for the game against the Vikings is also in doubt.
Cam Akers | RB

Pickup
Week 5
- Expected to take over as the early-down back if Mixon and Pierce are both unable to play.
Houston Texans

- Facing injury concerns with key running backs Joe Mixon and Dameon Pierce.
- Potential for Cam Akers and Dare Ogunbowale to step up in their absence.