The San Francisco 49ers are facing a two-game losing streak and are monitoring the injury statuses of key players ahead of their matchup against the New England Patriots. Tight end George Kittle is set to return after recovering from a hamstring strain, while receiver Deebo Samuel is questionable due to a calf injury. Left tackle Trent Williams has also been added to the injury report with a toe issue. The team is hopeful for Samuel's return, which would be a pleasant surprise given his recent injury timeline. Additionally, running back Christian McCaffrey is on injured reserve but could ramp up his rehab soon.
- George Kittle is back from injury and ready to play.
- Deebo Samuel's status is uncertain but shows positive signs.
- Trent Williams' injury adds concern to the offensive line.