49ers wide receiver Deebo Samuel is set to play against the New England Patriots despite earlier indications that he would miss a couple of weeks due to a calf injury. After limited practices leading up to the game, Samuel's return adds depth to the 49ers' receiving corps, which may impact the fantasy value of other players like Jauan Jennings. With Samuel and tight end George Kittle back in action, fantasy managers should consider the implications for their lineups.

• Deebo Samuel's unexpected return could affect other players' fantasy value.
• Soft-tissue injuries carry a risk of aggravation during games.