The Detroit Lions upset the Kansas City Chiefs, winning 21-20 in the NFL season opener. Lions' quarterback Jared Goff had a strong performance, extending his streak of consecutive passes without an interception to 359, the third-longest in NFL history. Rookie defensive back Brian Branch scored a pick-six, becoming the first Lions player to score a defensive touchdown in his first career game since 2009. The Chiefs struggled on offense without tight end Travis Kelce, who was injured, and their rushing game was ineffective. Despite this, quarterback Patrick Mahomes completed passes to 11 different receivers and led a touchdown drive late in the first half.

• The Lions ended their winless streak in season openers and got their first 1-0 start since 2017.
• Amon-Ra St. Brown is a reliable target for Jared Goff and reached 200 receptions in his first three NFL seasons.
• Brian Branch had a breakout performance with a pick-six in his first career game.
• Jared Goff had a strong performance, extending his streak of consecutive passes without an interception to 359, the third-longest in NFL history.
• The Chiefs struggled on offense without Travis Kelce and their rushing game was ineffective.
• Patrick Mahomes completed passes to 11 different receivers and led a touchdown drive late in the first half.