George Kittle, the tight end for the San Francisco 49ers, is listed as questionable for Week 1 due to a groin injury. He has been limited in practice this week and his availability for Sunday's game against Pittsburgh will likely be a game-time decision. If Kittle is unable to play or has reduced playing time, it could result in more targets for WRs Brandon Aiyuk and Deebo Samuel, as well as RB Christian McCaffrey in fantasy football.