Colts running back Jonathan Taylor will miss the upcoming game against the Jaguars due to an ankle injury. He did not practice throughout the week, making his availability for Week 6 uncertain. With Taylor sidelined, the Colts will rely on a committee approach featuring Trey Sermon and Tyler Goodson, with the possibility of Evan Hull being elevated from the practice squad. Head coach Shane Steichen indicated that Sermon is expected to lead the backfield but should be considered a low-end RB3 or Flex option in fantasy lineups.
- Jonathan Taylor's absence significantly impacts the Colts' backfield strategy.
- Sermon is expected to lead the committee but is not a strong fantasy starter.