Isaac Guerendo, running back for the San Francisco 49ers, was listed as a non-participant on Monday's estimated injury report due to a foot sprain sustained during his first career start against the Bears. Despite an impressive performance with 128 yards from scrimmage and two rushing touchdowns, his status for Week 15 against the Rams is uncertain. Coach Kyle Shanahan indicated that Guerendo's injury may not be serious, but further evaluation is needed as the team prepares for a quick turnaround.

• Guerendo had a strong performance before his injury, showcasing his potential as a starter.
• The 49ers may need to rely on backup options if Guerendo is unable to play in Week 15.