The Detroit Lions faced a tough loss against the Buffalo Bills, not only losing the game 48-42 but also suffering significant injuries to key defensive players. Starting defensive tackle Alim McNeill has been ruled out for the season due to a torn ACL, while cornerback Carlton Davis III will undergo surgery for a fractured jaw and will be sidelined indefinitely. These injuries add to the Lions' defensive woes, with multiple players already on injured reserve, including star defensive end Aidan Hutchinson.

• The Lions' defense is facing a crisis with multiple key injuries.
• Despite the loss, the Lions maintain a strong position in the NFC playoff race.