San Francisco 49ers running back Christian McCaffrey will not return to practice next week due to an Achilles injury, meaning he will miss at least one more game. This situation leaves the 49ers with either Jordan Mason or Isaac Guerendo as the lead backs for their upcoming game against the Chiefs. McCaffrey's injury has raised the possibility of him being placed on injured reserve, which would require him to miss at least four games.
- McCaffrey's absence will significantly impact the 49ers' backfield strategy.
- The team may need to consider their options for the lead back role moving forward.