Commanders QB Jacoby Brissett is unlikely to play against the 49ers due to a hamstring injury. The team will evaluate his condition during pre-game warmups before making a final decision. In his absence, Sam Howell will start at quarterback for the Commanders. Howell has struggled in the past two weeks and is not a reliable option for fantasy lineups in Week 17.

• Jacoby Brissett is unlikely to play due to a hamstring injury
• Sam Howell will start at quarterback for the Commanders
• Howell has struggled in the past two weeks and is not a reliable fantasy option