San Francisco 49ers running back Isaac Guerendo has been ruled out for Week 16 due to a hamstring injury. He did not practice this week and is expected to miss time beyond Sunday. With Guerendo sidelined, Patrick Taylor and Israel Abanikanda are set to lead the backfield for the 49ers, with Ke'Shawn Vaughn likely being called up from the practice squad.
- Guerendo's absence could impact the 49ers' running game significantly.
- Patrick Taylor and Israel Abanikanda are expected to share the workload.
Isaac Guerendo | RB
Injury
Week 16
- Ruled out for Week 16 due to a severe hamstring injury.
- Did not practice leading up to the game.
Patrick Taylor | RB
Pickup
Week 16
- Expected to take on a larger role in Guerendo's absence.
- Filled in as lead back in Week 14 when Guerendo was injured.
Israel Abanikanda | RB
Pickup
Week 16
- Also expected to share carries with Taylor.
- Could see increased usage with Guerendo out.
Ke'Shawn Vaughn | RB
Pickup
Week 16
- Likely to be elevated from the practice squad for Week 16.
- Could provide depth in the backfield.
San Francisco 49ers
- Dealing with multiple injuries in the running back position.
- Will rely on Taylor and Abanikanda to fill the gap left by Guerendo.