Aiyuk (shoulder) doesn't have an injury designation for Sunday's game against the Cardinals. Aiyuk has been practicing all week and might've been able to play in last week's game if the Niners had played on Sunday instead of Thursday. Facing a vulnerable defense without Samuel in the lineup is a best-case scenario for Aiyuk's expected production, though he still has sturdy touch/target competition coming from TE George Kittle and RB Christian McCaffrey.