San Francisco 49ers running back Christian McCaffrey is uncertain to play in Week 2 due to ongoing Achilles tendinitis and a calf strain. General Manager John Lynch indicated that McCaffrey's condition is unpredictable, suggesting that he may be listed as questionable again. In McCaffrey's absence, Jordan Mason had a standout performance, rushing for 147 yards and a touchdown in the team's recent victory over the Jets.
- McCaffrey's injury situation remains fluid and he may miss another game.
- Jordan Mason has proven to be a capable replacement, showcasing strong performance.