The Seattle Seahawks are set to place outside linebacker Uchenna Nwosu on injured reserve due to a thigh injury, which will sideline him for at least the next four games. Nwosu, who is considered the Seahawks' best edge defender, had recently returned from a long injury layoff but will now miss additional time. The team is also facing potential absences of other key defensive players as they prepare for an upcoming game against the San Francisco 49ers.

• Uchenna Nwosu's injury is a significant blow to the Seahawks' defense.
• The Seahawks are struggling with multiple injuries as they face a tough matchup against the 49ers.