The San Francisco 49ers will start Brandon Allen at quarterback against the Green Bay Packers due to Brock Purdy's shoulder injury. This marks the first time Purdy has missed a start since becoming the 49ers' quarterback in December 2022. Additionally, star defensive end Nick Bosa will also miss the game due to injuries, while left tackle Trent Williams is questionable.
- Brock Purdy's absence is significant as he has been a key player for the 49ers since taking over as starting QB.
- Brandon Allen will make his first start for the 49ers, having experience as a starter in previous seasons.