The San Francisco 49ers faced a significant setback as defensive tackle Javon Hargrave suffered a partially torn right triceps during their recent game against the Los Angeles Rams. This injury will require surgery and is likely to end his season. Coach Kyle Shanahan expressed disappointment over the loss, noting Hargrave's strong performance prior to the injury. Additionally, quarterback Brock Purdy is dealing with back soreness but is day-to-day, while running back Christian McCaffrey is seeking treatment for persistent Achilles tendonitis in Germany. The 49ers are also hoping to get tight end George Kittle back in practice soon.

• Javon Hargrave's injury is a major blow to the 49ers' defense.
• Brock Purdy's back soreness adds to the team's injury woes.
• Christian McCaffrey's ongoing Achilles issues raise concerns about his return.