The Indianapolis Colts are facing uncertainty in their backfield as both Jonathan Taylor and Trey Sermon missed practice on Wednesday due to injuries. Head Coach Shane Steichen expressed optimism about Taylor's recovery but fantasy owners should not rely on him for Week 6. If both Taylor and Sermon are unable to play, Tyler Goodson is set to take on the starting role against the Titans.
- Jonathan Taylor's status for Week 6 is uncertain, making him a risky play for fantasy owners.
- Trey Sermon's injury adds to the Colts' backfield woes, leaving Tyler Goodson as a potential starter.