Isaac Guerendo, running back for the San Francisco 49ers, suffered a possible foot sprain during a recent game against the Bears, where he had an impressive performance with 128 scrimmage yards and two touchdowns. With key players like Christian McCaffrey and Jordan Mason already sidelined, Guerendo was expected to take on a larger role in the 49ers' backfield. However, his injury raises concerns about his availability for upcoming games, particularly against the Rams.
- Issac Guerendo's potential foot sprain could impact the 49ers' backfield depth.
- With multiple injuries in the running back position, Guerendo's role was set to increase significantly.