Pittsburgh Steelers running back Jaylen Warren has been ruled out for the upcoming game against the Indianapolis Colts due to a knee injury. He did not practice this week and is targeting a return on October 6 against the Dallas Cowboys. In his absence, Cordarrelle Patterson is expected to see increased opportunities behind Najee Harris, with potential elevations from the practice squad.
- Jaylen Warren's knee injury will keep him out for Week 4.
- Cordarrelle Patterson will likely take on a larger role in the backfield.