In a dominant performance, the Detroit Lions defeated the Jacksonville Jaguars 52-6, marking their largest margin of victory in franchise history. However, the victory was overshadowed by the loss of linebacker Alex Anzalone, who will be sidelined for 6-8 weeks due to a broken forearm. Despite the injury setbacks, the Lions showcased their offensive prowess, achieving a franchise-best 645 total yards and scoring touchdowns on seven consecutive drives. Quarterback Jared Goff made history with a perfect passer rating and over 400 passing yards.
- Lions set franchise records for margin of victory and total first downs.
- Goff's performance solidifies his place in NFL history with multiple perfect passer rating games.