In the Fantasy Football Playbook for Week 16, Mike Clay provides insights into player projections, matchups, and lineup decisions for fantasy football enthusiasts. The article emphasizes the importance of understanding player performance metrics and offers advice tailored for 12-team PPR leagues. With the Broncos facing the Chargers, the guide aims to assist in critical sit/start decisions and waiver wire strategies as the fantasy playoffs approach.

• Focus on matchup-based analysis for optimal player performance.
• Utilize projections for informed sit/start decisions in fantasy leagues.