San Francisco 49ers running back Isaac Guerendo is set to play against the Los Angeles Rams despite dealing with a sprained foot. Guerendo, who has stepped up as the starting running back due to injuries to key players, had an impressive performance last week, rushing for 78 yards and two touchdowns while also contributing in the passing game. The 49ers are facing a critical matchup as they aim to stay in the playoff hunt.
- Guerendo's performance has been pivotal for the 49ers with multiple key injuries in the backfield.
- The 49ers need a win against the Rams to keep their playoff hopes alive.