Colts right guard Will Fries suffered a serious tibia injury during a game against the Jaguars and will require surgery. The injury occurred while Fries was blocking for running back Trey Sermon, leading to a potential fracture. This injury adds to the Colts' mounting injury woes, including sidelined quarterback Anthony Richardson and running back Jonathan Taylor. The Colts lost the game 37-34, marking their 10th consecutive road loss to the Jaguars.
- Will Fries' injury is a significant blow to the Colts' offensive line.
- The Colts continue to struggle with injuries to key players.