The Houston Texans will be missing their leading rusher, Joe Mixon, in Week 3 due to an ankle injury sustained during their Week 2 victory over the Chicago Bears. Mixon, who ranks seventh in the NFL in rushing yards this season, will not travel with the team for their game against the Minnesota Vikings. Cam Akers is expected to take over the bulk of the carries in Mixon's absence. Akers, who previously played for the Vikings, has shown promise in his limited opportunities.
- The Texans will be without both Joe Mixon and backup Dameon Pierce for their upcoming game.
- Cam Akers is set to step up as the primary running back, having shown capability in previous games.