San Francisco 49ers running back Isaac Guerendo is set to return to action on Monday night against the Detroit Lions after missing last week due to a hamstring injury. Guerendo's return comes at a crucial time as the 49ers have been dealing with multiple injuries in their backfield. He has shown promise in his previous games, rushing for a total of 135 yards over two weeks before his injury. With Guerendo back, the 49ers will have additional depth at running back as they look to bounce back against the Lions.
- Isaac Guerendo is returning from injury just in time for a key matchup against the Lions.
- The 49ers have faced significant injuries at the running back position, making Guerendo's return vital.